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Ed learn more ✅ Erectile Dysfunction: A Science-Based Guide Erectil e dysfunction (ED) is the persistent inability to achieve or maintain an erection sufficient for sexual performance. It affects an estimated 30 million men in the U.S. and over 150 million worldwide [1]. Understanding its causes is essential for prevention and treatment. 1. Medical Conditions and Chronic illnesses can damage blood vessels, nerves, and hormones that regulate erections. Diabetes is one of the strongest risk factors, increasing ED prevalence by up to 3-fold [2]. Cardiovascular disease and hypertension reduce blood flow to the penis, impairing erectile function [3 Hormonal imbalances (e.g., low testosterone) can lead to decreased libido and erectile difficulties [4]. 🧠 2. Psychological Causes ED is not only physical—it often has psychological roots. Depression and anxiety disrupt sexual desire and performance [5]. Stress, performance fears, and relationship conflicts contribute ...